Do We Have a Biocompatible Peritoneal Dialysis Fluid?

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Effects of biocompatible versus standard fluid on peritoneal dialysis outcomes.

The clinical benefits of using "biocompatible" neutral pH solutions containing low levels of glucose degradation products for peritoneal dialysis compared with standard solutions are uncertain. In this multicenter, open-label, parallel-group, randomized controlled trial, we randomly assigned 185 incident adult peritoneal dialysis patients with residual renal function to use either biocompatible...

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Biocompatible peritoneal dialysis solutions: do they indeed affect the outcome?

Numerous studies have confirmed beneficial effects of polyglucose dialysis solution (PG-DS), an amino acid dialysis solution (AA-DS), and bicarbonate (bic) or bicarbonate/lactate (bic/lac) buffered solutions on selected components of peritoneal bioavailability or clinical parameters of peritoneal dialysis (PD) patients. Few adverse effects have also been described. A question arises whether the...

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Biocompatible Solutions for Peritoneal Dialysis

In 1978, a simplified technique for peritoneal dialysis (PD) using plastic bags and glucose as osmotic agent allowed PD to become accepted as a home-based renal replacement therapy. However, PD was marred by complications including peritonitis and loss of function of the peritoneal membrane. Both complications may be favored by the bioincompatibility of PD solutions. The composition of PD solut...

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Biocompatible Peritoneal Dialysis Fluids: Clinical Outcomes

Peritoneal dialysis (PD) is a preferred home dialysis modality and has a number of added advantages including improved initial patient survival and cost effectiveness over haemodialysis. Despite these benefits, uptake of PD remains relatively low, especially in developed countries. Wider implementation of PD is compromised by higher technique failure from infections (e.g., PD peritonitis) and u...

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Increased peritoneal permeability at peritoneal dialysis initiation is a potential cardiovascular risk in patients using biocompatible peritoneal dialysis solution

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ژورنال

عنوان ژورنال: Open Journal of Nephrology

سال: 2012

ISSN: 2164-2842,2164-2869

DOI: 10.4236/ojneph.2012.23005